Tax M. Georgiadis

Assistant Research Professor Synthetic & Medicinal Chemistry B.S., Indiana University-Bloomington, 1983. Ph.D., University of California-Los Angeles, 1989. Post-Doctoral, Columbia University, 1989- 1991; Columbia University College of Physicians & Surgeons, 1991-1993.   Phone:(317) 274-6804 Email:tgeorgia@iupui.edu Research Publications

 

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Research

My primary research interests lie in the area of medicinal chemistry. As a synthetic organic chemist with many years experience in drug discovery in the pharmaceutical industry, I use fragment-based lead discovery methods to identify and synthesize small molecule inhibitors useful in oncology research.

Recent Publications

R. J. Patch, B. M. Brandt, D. Asgari, N. Baindur, N. K. Chadha, T. Georgiadis, W. S. Cheung, I. P. Petrounia, R. R. Donatelli, M. A. Chaikin and M. R. Player "Potent 2'- aminoanilide inhibitors of cFMS as potential anti-inflammatory agents" Bioorganic & Medicinal Chemistry Letters 2007, 17, 6070-6074.

T. M. Georgiadis, N. Baindur and M. R. Player "Solid-phase synthesis of an oxalic acid amide library" Journal of Combinatorial Chemistry 2004, 6, 224-229.

Recent Patent Applications

J. R. Garlich, D. L. Durden, T. M. Georgiadis, J. Su, X. Peng and T. C. Smith "Pten Inhibitors" U.S. Pat. Appl. Publ. 2007 , US 20070203098 A1.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. Georgiadis "C-Fms Kinase Inhibitors" PCT Int. Appl. 2006 , PCT/US2006/014886. Publ. No. WO/2007/123516.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. Georgiadis "C-Fms Kinase Inhibitors" U.S. Pat. Appl. Publ. 2006 , US 20060258666 A1.

J. R. Garlich, D. L. Durden, T. M. Georgiadis, J. Su, X. Peng and T. C. Smith "Preparation of (Heteroaryl) Amides and Hydrazides as Inhibitors of Phosphatase Located on Chromosome 10 (PTEN)" PCT Int. Appl. 2005 , PCT/US2005/011626. Publ. No. WO/2005/097119.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. M. Georgiadis "C-Fms Kinase Inhibitors" U.S. Pat. Appl. Publ. 2005 , US 20050131022 A1.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. M. Georgiadis "Inhibitor of C-Fms Kinase" PCT Int. Appl. 2005 , PCT/US2005/038307. Publ. No. WO/2006/047479.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. M. Georgiadis "Inhibitor of C-Fms Kinase" PCT Int. Appl. 2005 , PCT/US2005/038340. Publ. No. WO/2006/047503.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. M. Georgiadis "Inhibitors of C-FMS Kinase" U.S. Pat. Appl. Publ. 2005 , US 2005113566 A1.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. M. Georgiadis "C-Fms Kinase Inhibitors" U.S. Pat. Appl. Publ. 2005 , US 2005004112 A1.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. M. Georgiadis "C-Fms Kinase Inhibitors" PCT Int. Appl. 2004, PCT/US2004/012729. Publ. No. WO/2004/096795.

Recent Patents

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. Georgiadis "C-Fms Kinase Inhibitors" US 7,429,603; Issued: Sept. 30, 2008.

M. R. Player, N. Baindur, B. M. Brandt, N. Chadha, R. J. Patch, D. Asgari and T. Georgiadis "C-Fms Kinase Inhibitors" US 7,427,683; Issued: Sept. 23, 2008.

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